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Anavex reports long-term Alzheimer's data for drug with history of scrutiny

Anavex Life Sciences is back with more data for a pill that it’s looking to get approved in a variety of neurodegenerative and CNS disorders, reporting long-term Phase 2/3 Alzheimer’s data Monday. The...

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Can the Pfizer machine fight back against an activist investor?

Pfizer says it’s back on track. After a tumultuous 2024 filled with more cost cuts, an activist investor, a pulled drug and executive changes, CEO Albert ...

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FTC goes after pharma middlemen's price hikes on 'specialty' drugs

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Regeneron, Illumina invest in Truveta; Inhibrx Bio’s $150M loan

Plus, news about Bioptimus, RhyGaze, Grifols, subcutaneous Leqembi and Sling Therapeutics: Regeneron pours $119.5M into Truveta Series C: Regeneron will also work with the medical data research company...

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Australia's BioCina and NovaCina join forces to make one CDMO

Private investment firm Bridgewest is combining its Australia-based biologics CDMO BioCina and its sterile injectable manufacturer NovaCina into one company. The new CDMO will continue to use the...

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Regenxbio sells Hunter syndrome license with FDA filing underway

Nippon Shinyaku has paid $110 million upfront for the rights to sell two of Regenxbio’s gene therapies for mucopolysaccharidosis in the US and Asia. The deal also provides for potential milestone fees...

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Umoja’s $100M Series C will advance its bid for more convenient cell therapies

In the 10th megaround of 2025, Umoja Biopharma has banked $100 million in a Series C fundraise with an eye to advancing its pipeline of in vivo CAR-T cell therapies for cancer and autoimmune diseases ...

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Charles River offers damp 2025 outlook for investors

Charles River Laboratories is predicting 2025 to be as tough as last year for CDMOs as pharma customers continue to cut costs with manufacturers. The company expects its revenue for 2025 to decline in...

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Lykos upheaval continues with four new board exits

Four Lykos Therapeutics board members have stepped down, and another departed last month, in the aftermath of a stalemate over how to finance the psychedelic company's clinical future. The company...

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HHS inspector general raises concerns over three FDA accelerated approvals

The upheaval over the FDA's accelerated approval of Biogen's now-pulled Alzheimer's drug Aduhelm in 2021 led HHS' Office of Inspector General to review 24 other accelerated approvals to see if there...

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Eli Lilly misses 2024 revenue expectations, stock dips 7%

Eli Lilly expects to miss its recent revenue estimate for 2024 by about $400 million, according to a preliminary report. The company’s estimates have varied widely this year. Lilly raised its 2024...

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Samsung Bio eyes construction of sixth manufacturing plant to kickstart 2025

Following a blockbuster 2024, Samsung Biologics is considering building a sixth manufacturing facility to meet the rising demand for biologics as it gears up to open its fifth site in April. During the...

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#JPM25: Day 3 at the JP Morgan Healthcare Conference

It's day 3 of the JP Morgan Healthcare Conference, and it's started to get a little less crowded in San Francisco. That said, many small biotechs, pharma companies and manufacturers are still set to...

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OS Therapies plots expedited approval for osteosarcoma drug after Phase 2 win

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Hinge Bio's $30M raise; Keros reports additional issues in Phase 2 PAH trial

Plus, news about Inflammasome Therapeutics, Johnson & Johnson and Verastem: Autoimmune disease startup nabs $30M: Hinge Bio de-stealthed with a Series A on Wednesday, led by hedge ...

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Drugmakers again tout limits of IRA impact

Johnson & Johnson, AstraZeneca and Pfizer leaders reiterated during the JP Morgan Healthcare Conference that the federal government’s price negotiations still won’t have a material effect on their...

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FDA explains why it rejected Vanda's stomach drug in late 2024

Rarely does the FDA publicly release its reasoning for rejecting a potential new drug. But for DC-based Vanda Pharmaceuticals' gastroparesis drug, the FDA on Wednesday spelled out why it issued a CRL

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Vertex's fertility support bid is 'self-serving,' HHS says

The Department of Health and Human Services says Vertex is “grasping at straws” in a lawsuit challenging the agency’s decision to reject its proposed fertility support for certain gene therapy...

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DEA issues proposed rule to permanently expand online prescribing of...

The Drug Enforcement Administration on Wednesday issued a long-awaited proposed rule that would create a permanent process for clinicians to more easily prescribe controlled drugs online. The proposal...

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Eli Lilly's Omvoh earns FDA approval for Crohn's disease

The FDA approved Eli Lilly’s Omvoh in Crohn’s disease, the company announced Wednesday, handing the drug its second indication after giving it a green light for ulcerative colitis in late 2023. While...

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