Repare to lay off 75% of staff; Castle Creek inks $75M royalty deal
Plus, news about BioCity Biopharma, Kiniksa, Inceptor Bio, Ryvu Therapeutics, RedHill, VarmX, Paradox Immunotherapeutics and Lava Therapeutics: Repare Therapeutics lays off 75% of staff: The biotech in...
View ArticleLilly pays $10M upfront for Organovo’s FXR agonist program
Eli Lilly is buying Organovo’s farnesoid X receptor (FXR) agonist program, which includes a drug in Phase 2 development for ulcerative colitis and metabolic dysfunction-associated steatohepatitis...
View ArticleIndian drugmakers join forces to boost national biomanufacturing sector
Several contract research, development and manufacturing organizations based in India are banding together to form a trade group with an aim to bolster the nation’s production footprint and talent...
View ArticleThermo Fisher buys Solventum's purification business for $4.1B
Thermo Fisher Scientific is spending $4.1 billion in cash to acquire US healthcare company Solventum’s purification and filtration business, along with its 2,500 employees. The manufacturer expects the...
View ArticleChinese ADC biotech lets Hong Kong IPO filing lapse
Duality Biologics, an ADC startup that's attracted multiple biopharma partnerships, has let its plans to list on the Hong Kong Stock Exchange fizzle out. The Shanghai-based biotech's
View ArticleJ&J seeks to stop Samsung Bioepis from licensing Stelara biosimilar
Johnson & Johnson is suing Samsung Bioepis for allegedly breaching the terms of a contract regarding the launch of the Korean biotech’s Stelara biosimilar. The lawsuit, filed Monday in federal...
View ArticleBoehringer Ingelheim wins jury verdict in Zantac retrial in Illinois
An Illinois jury ruled in favor of Boehringer Ingelheim in Zantac litigation brought by two prostate cancer patients, the company confirmed. The verdict followed two mistrials in ...
View ArticleEmalex clears Phase 3 for Tourette syndrome, will seek FDA approval
Emalex Biosciences said its daily oral tablet helped reduce relapses for children and adults with Tourette syndrome in a Phase 3 study, and now plans to take the drug to regulators for approval. The...
View ArticleCompounders sue FDA over end of semaglutide shortage
Drug compounders have sued the FDA to put the weight loss and diabetes drug semaglutide back on an official shortage list, fighting a regulatory decision that imperils the companies' business. “If ever...
View ArticleCandel's viral therapy shows promising survival in small pancreatic cancer study
To Candel Therapeutics CEO Paul Peter Tak, the biotech’s viral immunotherapy has passed the "bloody obvious test" in pancreatic cancer, and it’s preparing to start a larger trial next year. The biotech...
View ArticleLeo Pharma says its yearslong makeover is about to pay off
For the first time since 2018, dermatology-focused Leo Pharma projects that it could turn a profit this year. Its Wednesday guidance comes on the heels of a broad multiyear restructuring — a plan ...
View ArticleCourt orders CVS to comply with the FTC’s PBM-related investigation
The Federal Trade Commission is continuing its investigation into anticompetitive PBM practices, with a new court order that will require CVS Health to share more requested documents about its PBM....
View ArticleEikon raises $351M Series D, pipeline advances to Phase 3
One of biotech's best-funded startups has just raised a huge new round to take its lead drug into final-stage testing. On Wednesday, Eikon Therapeutics announced a $351 million Series D round, one of...
View ArticleMerck says Keytruda could be up next for IRA price cuts
Merck said its “once-in-a-lifetime” drug Keytruda could be subject to price reductions under the Inflation Reduction Act, which would lead to a decline in sales. It expects Keytruda to be chosen for ...
View ArticleGinkgo uncertain over the future of US government funding, stock drops
Ginkgo Bioworks’ stock $DNA fell by around 13% premarket Wednesday after the company dampened its 2025 sales forecast. “We are being conservative with our revenue guidance in 2025 given uncertainty...
View ArticleUpdated: Lilly joins Trump administration to announce $27B manufacturing...
WASHINGTON — Eli Lilly touted a huge new US manufacturing investment at an event on Wednesday, trotting out the news with a member of President Donald Trump’s cabinet as part of what has been a...
View ArticleHarbour BioMed inks deal up to $395M; ORIC refines plans for two drugs
Plus, news about Idorsia, Enveda, Zymeworks, BerGenBio and Ignota Labs: Harbour BioMed does another deal: The Shanghai-based biotech’s subsidiary, called HBM Alpha Therapeutics, inked a pact with an...
View ArticleRegeneron, two Chinese biotechs tout promise of their hearing loss gene...
Several small clinical trials have demonstrated that gene therapies have restored hearing in children with a rare form of genetic deafness. In an update at the Association for Research in...
View ArticleAstraZeneca’s SERD hits primary endpoint in late-stage trial, but first-line...
AstraZeneca wasn't expected to have data from the Phase 3 trial of its oral SERD until the second half of this year so the positive interim results that the UK drugmaker
View ArticleRegeneron shakes up accelerated approval plans for lymphoma bispecific
Regeneron is now expecting an accelerated approval decision this summer on its T cell engager for one form of lymphoma, while it's giving up on accelerated approval for a different form of the disease....
View Article