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How Akido Labs uses AI to run medical visits, from intake to diagnosis

For cardiologist Haritha Alla, a typical day in her Los Angeles-area clinic is ruled by mundane data collection. Patients struggle to fill out intake forms and tend to leave them unfinished. Much of...

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Sanofi to pay $600M upfront for Dren Bio’s bispecific B cell depleter

Sanofi is buying a B cell-depleting antibody developed by Dren Bio as a therapy for cancer and autoimmune diseases. The pharma said on Thursday that it will pay $600 million in ...

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Paratek to acquire Optinose and its nasal spray Xhance

Paratek Pharmaceuticals is expanding beyond antibiotics and infectious disease by paying up to $330 million to acquire Optinose and its drug-device combination for chronic rhinosinusitis (CRS). Paratek...

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Monte Rosa reports first data for molecular glue program

Monte Rosa Therapeutics reported Phase 1 data Thursday morning for a Novartis-partnered program that the companies believe could change the treatment paradigm for some immune-mediated diseases. Though...

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Illumina's CEO evolves strategy with multiomics push

SAN DIEGO — At the headquarters of Illumina last week, CEO Jacob Thaysen bounded up a coiled staircase that mimics a DNA strand. The architectural flourish at the company’s campus is a representation...

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UnitedHealth's Optum Rx to change its payment models

UnitedHealth Group's pharmacy benefit manager Optum Rx is making changes to its payment models. Optum Rx will tweak its payment models in full force by January 2028 to more closely reflect the high...

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Elevation Oncology stops work on ADC, lays off workers; AstraZeneca’s CEPI...

Plus, news about Century Therapeutics, Akebia Therapeutics, Eyenovia, Betaliq, Alvotech, Genenta Science, Aadi Bioscience, and Exicure: Elevation Oncology drops ADC, lays off 70%: The Boston-based drug...

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Merck to lay off 163 workers in Pennsylvania; Delpharm gets $60M from...

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Merck plans to lay off 163 staffers as it closes its facility in...

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Visen Pharmaceuticals prices $86M Hong Kong IPO

Visen Pharmaceuticals, a biotech developing much of Ascendis Pharma’s endocrine-related disease pipeline for the China market, will go public on the Hong Kong Stock Exchange on Friday. The company...

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Google is building AI healthcare helpers

It feels like people have gotten a lot more comfortable with using AI day to day. Every spring, I go to Google’s office in New York to see how the tech giant’s applying its technology ...

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SV Health Investors nabs $250M to fund dementia-focused biotechs

SV Health Investors has added $250 million to its hunt for new therapeutics for dementia, Alzheimer's and other neurodegenerative diseases. The London-based life sciences investor secured that amount...

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Calley Means joins White House as a special government employee

A close ally of HHS Secretary Robert F. Kennedy Jr. is joining the administration as a special government employee, according to a source familiar with the decision. Calley Means, an entrepreneur and...

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Novo Nordisk lays out new structure for early R&D unit

Novo Nordisk is reorganizing its research and early development unit in an effort to “future-proof the organization” and “significantly increase” the number of projects it brings into clinical trials,...

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Many rare disease drugs rely on just one trial for approval, FDA authors find

New research published by FDA authors found that 67% of non-oncologic rare disease marketing applications approved between 2020 and 2023 used only one clinical trial plus confirmatory evidence to...

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Akero exec calls MASH accelerated approval guidance 'bizarre'

NEW YORK — Akero Therapeutics may not have adequate data for accelerated approval of its MASH drug, despite showing it may reverse cirrhosis in patients with severe liver disease. The problem, chief...

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ACIP meeting, delayed earlier this year, is rescheduled

A meeting of CDC vaccine advisors that’s been in limbo for almost a month is slated to take place around the middle of April, two sources familiar with the planning told Endpoints News. A spokesperson ...

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FDA approves Alnylam’s Amvuttra in ATTR-CM, kicking off competition with...

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BridgeBio, Editas finance chiefs depart; Former FDA No. 2 joins Recursion's...

→ Brian Stephenson has stepped down after more than five years as CFO of BridgeBio, and president Tom Trimarchi will take over. Trimarchi was promoted to president and COO last July. “It has been an ...

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Exclusive: VantAI builds AI model Neo-1 for molecular glues

A Roivant Sciences spinout says it has made the first AI model, to its knowledge, that simultaneously predicts biomolecule structures while generating new molecules. The diffusion-based model, called...

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Johnson & Johnson earmarks $55B to boost US capacity 

Johnson & Johnson is planning to invest $55 billion to build up its US footprint over the next four years, becoming the latest pharma company to pour billions into the country. As a part of ...

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